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How Long Does It Take For Alpha GPC To Work?
Mar 21, 2018

What Is It?

Alpha Glycerylphosphorylcholine better known as Alpha GPC is a form of choline that is used for enhancing cognitive performance and increasing power output via its influence on growth hormone production.


Alpha GPC is both a source of phospholipids and choline and is utilized for phosphatidylcholine (PC) biosynthesis in the brain and the production of acetylcholine, the chemical that allows for brain cells to communicate with each other. 

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What Does It Do?

Alpha GPC quickly crosses the blood-brain barrier where it protects neurons and improves brain function and learning processes. Specifically by mechanism of action Alpha GPC directly increases the synthesis and secretion of acetylcholine better than any other choline related compound, influencing both system-wide and brain concentrations of choline.


Alpha GPC is effective for enhancing mental performance and improving memory and learning ability by counteracting the age-related loss of nerve cells and fibers in the brain.


In addition some preliminary evidence suggests that Alpha GPC has the ability to enhance acute growth hormone production and power output during exercise. An increase in growth hormone production and power output has the ability to increase muscle mass and improve overall metabolic activity resulting in improved body composition. 


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When Do I Take It?

To take advantage of the cognitive enhancement and power output properties of Alpha GPC, it is best taken 15-20 minutes before exercise. Pure form Alpha GPC capsules or powder can be mixed with water, or with any other type of supplement and consumed. 


As an emerging supplement the most efficacious dose of Alpha GPC is between 500mg-1200mg per day, typically broken into 3 separate doses throughout the day. Studies also report that larger single doses of 600mg-800mg may be more beneficial when Alpha GPC is to be taken before exercise such as in pre workout supplements. 


How Long Does It Take To Work?

Alpha GPC can quickly increase the synthesis of acetylcholine and neurotransmission in the brain, which is typically 20-30 minutes after oral consumption. Users can expect to experience an increase in mental alertness, concentration and mental focus within this timeframe. Consistent use in conjunction with a sensible diet and workout regime will experience the full performance and cognitive enhancing effects of Alpha GPC  within the first 2 weeks of use.


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